The effects of family-centered affective stimulation on narcotic poisoning comatose patients’ level of consciousness and cortex activity

Phase 3

Recruiting

Conditions: injury, poisoning and certain other consequences of external causes
Coma caused by opium poisoning.
(S00-T98)

Registration Number: IRCT20180930041185N2

Lead Sponsor: ational Institute of Medical Research Development (NIMAD)

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 90

Inclusion Criteria

Affliction by opium poisoning
A Glasgow Coma Scale (GCS) score of 5–8
Age of 18–65 year

Exclusion Criteria

Patients who discharged from the ICU
Death for any reason
Needed an emergency therapeutic intervention
Other poisoning in addition to narcotic drugs
Stroke or other cerebral events
History of CVA and drug abuse
Use of psychiatric drugs during the study

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The score of consciousness level is measured by the GCS scale and patients are selected with a score of 5 to 8. Post-intervention level of consciousness score can range from 3 to 15 which is measured and recorded by the research fellow nurses. Timepoint: Twice a day (morning and evening) up to 7 days. Method of measurement: Before and after intervention by a fellow nurse.;Cortical activity recorded by EEG is interpreted and analyzed by a neurologist.EEG signals will be recorded with a digital 26-channel scalp EEG device (g.tec, Guger Technologies, Graz, Austria), using the international 10-20 system. The EEG data will be acquired with a linked ear reference, sampled at 256 Hz with filter between 0.1Hz and 40Hz. Timepoint: Once a day every 7 days. Method of measurement: Every day before and after the intervention (morning shift) every 7 days.

Secondary Outcome Measures