A pilot study of dose schedules for pamidronate infusions in the management of non-specific low back pai

Phase 4

Completed

• Conditions: non-specific Low back Pain; Anaesthesiology - Pain management; Musculoskeletal - Other muscular and skeletal disorders

• Registration Number: ACTRN12615001193561
• Lead Sponsor: Tauranga Hospital. Bay Of Plenty DHB

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-11-04
• Study Completion: 2020-03-17
• Last Update Posted: 11 October 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Patients referred to chronic pain clinic at Tauranga Hospital.
Chronic non specific low back pain of at least three months duration
Pain score greater than 4 on numerical rating scale

Exclusion Criteria

Primary diagnosis of radicular or neuropathic pain
Vertebral compression fracture or cancer
Allergy to pamidronate
Significant other medical problems (renal, liver, cardiac, respiratory)
History of alcohol or drug abuse
Pending legal or compensation claim
Planned surgery or significant intervention in next six months

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Proportion of patients who show an improvement in Pain Scores measured on the Brief Pain Inventory (short form)<br>[90 days post infusion- primary time point<br>180 days post infusion- secondary time point- completion of study]

Secondary Outcome Measures

Name	Time	Method
Global impression of change(Quality of life)<br>[six months post first infusion dose]