NCT04588675Unknown不适用
Assessment of Myocardial Viability by Cardiac Magnetic Resonance Feature Tracking at Rest and During Stress by Low Dose Dobutamine
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 50
- 主要终点
- comparison of myocardial strain with late gadolinium enhancement
研究概览
简要总结
The aim of this study is to assess the diagnostic accuracy of CMR feature-tracking (FT) at rest & during stress with low dose dobutamine (LDD) in the evaluation of viability in ischemic cardiomyopathy (ICM) patients and compare it with delayed gadolinium enhancement (DGE).
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 20 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •All patients recruited into the study have chronic LV systolic dysfunction due to coronary artery disease (CAD)
排除标准
- •All patients with a contraindication to MR study:
- •Patients with implanted non-MRI compatible electronic devices (e.g. Cardiac pacemakers, intracranial metallic clips, implanted hearing aids, etc.)
- •Patients with foreign bodies in the eye.
- •Claustrophobic patients.
- •Patients diagnosed with recent acute coronary syndrome within 4 weeks.
- •Patients who had contraindications for MRI or contrast agents, and those with poor image quality due to either inadequate breath holding or arrhythmias
结局指标
主要结局
comparison of myocardial strain with late gadolinium enhancement
时间窗: Baseline
analysis of the myocardial strain by low dose dobutamine and test if it can assess myocardial viability
次要结局
未报告次要终点
研究者
Abdulrahman Emam Eldeen
Principal Investigator
Assiut University
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