NCT02366299
Withdrawn
Phase 4
Comparison of Sedative Effects of Dexmedetomidine and Propofol on the Clinical Course of Delirium and Neuroinflammation in Patients With SIRS.
Moscow Regional Research and Clinical Institute (MONIKI)0 sitesFebruary 2015
Overview
- Phase
- Phase 4
- Intervention
- Dexmedetomidine
- Conditions
- Delirium
- Sponsor
- Moscow Regional Research and Clinical Institute (MONIKI)
- Primary Endpoint
- CAM-ICU scale
- Status
- Withdrawn
- Last Updated
- 6 years ago
Overview
Brief Summary
Assessment of sedative effects of dexmedetomidine and propofol on the clinical course of delirium and neuroinflammation in patients with SIRS using CAM-ICU scale and protein S100b in serum.
Investigators
Valery V. Likhvantsev, Professor
senior researcher
Moscow Regional Research and Clinical Institute (MONIKI)
Eligibility Criteria
Inclusion Criteria
- •presence of delirium
Exclusion Criteria
- •presence of Alzheimer's disease
- •any mental disorder
- •presence of cancer
Arms & Interventions
dexmedetomidine
Treatment of delirium by dexmedetomidine i.v. infusion
Intervention: Dexmedetomidine
propofol
Treatment of delirium by propofol i.v. infusion
Intervention: Propofol
Outcomes
Primary Outcomes
CAM-ICU scale
Time Frame: up to 5 days
Similar Trials
Completed
Phase 4
Dexmedetomidine Versus Propofol for Sedation During Awake Endotracheal IntubationSedationIntubationNCT04753515Sixth Affiliated Hospital, Sun Yat-sen University100
Unknown
Phase 4
Effects of Dexmedetomidine Sedation on Delirium and Haemodynamic in Mechanical Ventilated Elderly PatientsSafety of Dexmedetomidine SedationNCT02225210Fuling Central Hospital of Chongqing City80
Recruiting
Phase 4
The Sedative Effects of Dexmedetomidine VS Propofol During Peribulbar Anesthesia in Patients Undergoing Vitrectomy SurgeryPatientSatisfactionNCT06369103Beni-Suef University420
Not yet recruiting
Not Applicable
Comparing two medicines for putting a tube in the windpipe for breathing in patients whose mouth does not open fullyCTRI/2020/03/023678Rajiv Gandhi Cancer Institute and Research Centre
Completed
Phase 4
Comparison of Remimazolam and Dexmedetomidine for Intraoperative SedationOrthopedic DisorderNCT05447507Seoul National University Hospital104