Comparison of Dexmedetomidine and Propofol on the Delirium and Neuroinflammation in Patients With SIRS.

Phase 4

Withdrawn

• Conditions: Delirium
• Interventions: Drug: Dexmedetomidine; Drug: Propofol

• Registration Number: NCT02366299
• Lead Sponsor: Moscow Regional Research and Clinical Institute (MONIKI)

Brief Summary

Assessment of sedative effects of dexmedetomidine and propofol on the clinical course of delirium and neuroinflammation in patients with SIRS using CAM-ICU scale and protein S100b in serum.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2015-01-26
• Study Start: 2015-02
• Study First Submitted QC: 2015-02-11
• Study First Posted: 2015-02-19
• Primary Completion: 2018-12
• Study Completion: 2018-12
• Status Verified: 2019-08
• Last Update Submitted: 2019-08-13
• Last Update Posted: 2019-08-14

Recruitment & Eligibility

• Status: WITHDRAWN
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• presence of delirium

Exclusion Criteria

• presence of Alzheimer's disease
• any mental disorder
• presence of cancer

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
dexmedetomidine	Dexmedetomidine	Treatment of delirium by dexmedetomidine i.v. infusion
propofol	Propofol	Treatment of delirium by propofol i.v. infusion

Primary Outcome Measures

Name	Time	Method
CAM-ICU scale	up to 5 days