MedPath

Meditation and Exercise to Treat Chronic Back Pain

Not Applicable
Completed
Conditions
Chronic Low Back Pain
Interventions
Behavioral: Control
Behavioral: Exercise and Meditation
Registration Number
NCT03324659
Lead Sponsor
Duquesne University
Brief Summary

This study evaluates the analgesic effect of a combination treatment of exercise and mindfulness based meditation in patients with chronic back pain. Half of the participants will partake in a 4-week exercise and meditation intervention, while the other half will receive a placebo treatment. The investigators hypothesize that a combination treatment reduces disability and pain more than the control intervention.

Detailed Description

Exercise and mindfulness based mediation can both produce analgesic effects in patients with chronic pain, but the mechanisms are not clear.

Combining treatments could produce analgesic effects that are additive, synergistic, or counteractive to each other. Here, the investigators examine the effects of a 4-week intervention in patients with chronic low back pain. Patients are assigned to a meditation/exercise group or a control group. The investigators will measure pain and disability using a variety of tools including surveys (disability, anxiety, mindfulness, and pain), pain VAS scales, and quantitative sensory testing.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
42
Inclusion Criteria
  1. Presence of clinically diagnosed nonspecific low back pain for at least 6 months
  2. Body mass index within the normal to overweight range (18.5-29.9)
  3. Resting heart rate 60 to 100 beats per minute
  4. Resting blood pressure less than or equal to 140/90
  5. Able to independently ambulate community distances without external support (e.g., walker, cane)
Exclusion Criteria
  1. Age less than 18 or greater than 60 years
  2. BMI ≥ 30 or ≤ 18.4
  3. Cardiovascular or respiratory disease
  4. Neurological disease, unrelated to low back pain
  5. Radicular low back pain
  6. Back pain associated with neuropathy
  7. Diabetes mellitus, Types 1 and 2
  8. Diagnosed with a chronic pain condition, unrelated to low back pain
  9. Acute pain
  10. Regular participation in high intensity athletic/sporting activities
  11. Sedentary lifestyle
  12. Currently pregnant
  13. Current cigarette smoker
  14. On-going litigation associated with back pain
  15. Inability to walk independently without external support (e.g. walker).
  16. Regular participation in meditation techniques or training in Mindfulness-based stress reduction

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
ControlControlThe Control group will listen to an audio book followed by quiet rest, five days per week for four weeks.
Exercise and MeditationExercise and MeditationThe Exercise and Meditation group will practice mindfulness meditation immediately before walking treadmill exercise, five days per week for four weeks.
Primary Outcome Measures
NameTimeMethod
Change in Roland Morris Disability Questionnairebaseline and 4 weeks

The Roland-Morris Disability Questionnaire is designed to assess self-rated physical disability caused by low back pain. The patient is asked to tick a statement when it applies to him that specific day, this makes it possible to follow changes in time. The end score is the sum of the ticked boxes. The score ranges from 0 (no disability) to 24 (max. disability).

Secondary Outcome Measures
NameTimeMethod
Change in Pressure Sensationbaseline and 4 weeks

Subjects will be examined using a pressure algometer to determine a pressure pain threshold, measured in Newtons

Change in Cutaneous Sensationbaseline and 4 weeks

Subjects will be examined using cutaneous sensory filaments on the forearm with data recorded in grams.

Fear Avoidance Beliefs Questionnairebaseline and 4 weeks

The Fear-Avoidance Beliefs Questionnaire (FABQ) is a questionnaire based on the Fear-Avoidance Model of Exaggerated Pain Perception, a model created in attempts to explain why some patients with acute painful conditions can recover while other patients develop chronic pain from such conditions. The FABQ measures patients' fear of pain and consequent avoidance of physical activity because of their fear. This questionnaire consists of 16 items, with each item scored from 0-6. Higher scores on the FABQ are indicative of greater fear and avoidance beliefs

Freiburg Mindfulness Inventorybaseline and 4 weeks

The FMI is a 14-item questionnaire for measuring mindfulness. It is most suitable in generalized contexts, where knowledge of the Buddhist background of mindfulness cannot be expected. The 14 items cover all aspects of mindfulness. The purpose is to characterize the experience of mindfulness. The subject is asked to answer every statement as honestly and spontaneously as possible. Each statement is scored on a 1 to 4 scale and a composite score is calculated from all statements.

VAS back pain (intensity & unpleasantness)baseline, daily (pre and post intervention), and 4 weeks

Participants will be asked to rate their current level of back pain intensity on a Visual Analog Scale (VAS) ranging from 0 to 10

State-Trait Anxiety Inventory (STAI)baseline and 4 weeks

The STAI is an introspective psychological inventory consisting of 40 self-report items pertaining to anxiety affect. It distinguishes between a person's state and trait anxiety levels. The A-Trait and A-State scales comprise 20 items each, scored on a 4-point Likert-type response scale. Higher STAI scores suggest higher levels of anxiety.

Change in Heat unpleasantnessbaseline and 4 weeks

Subjects will be examined using a heat block with a determined temperature threshold. Subjects will report unpleasantness using a VAS scale.

Trial Locations

Locations (1)

Duquesne University

🇺🇸

Pittsburgh, Pennsylvania, United States

© Copyright 2025. All Rights Reserved by MedPath