The 2-hour effects of whole-grain wheat in women with overweight or obesity
- Conditions
- Postprandial metabolic dysfunctionMetabolic and Endocrine - Metabolic disordersInflammatory and Immune System - Other inflammatory or immune system disorders
- Registration Number
- ACTRN12613000248763
- Lead Sponsor
- Victoria University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- Female
- Target Recruitment
- 15
Female
Overweight or obesity by waist circumference >80 cm or BMI > 25-35 kg/m2
Age 30-60 years
Participants with an allergy to wheat, gluten, dairy or lactose.
Pregnancy or lactation.
Smoking.
Liver, kidney or heart disease.
Type 1 diabetes and type 2 diabetes with insulin medication.
The use of any medication for weight loss.
Participants that do not regularly consume breakfast.
Unable to participate for 4-week period, including preliminary information visit and wash-out period.
Excessive exercisers, participating in regular physical activity in excess of moderate intensity and duration.
Participants with obesity caused by genetic factors or medication.
Neurological, endocrinological or other major systemic disease, including malignancy.
Acute illness or current evidence of acute or chronic inflammatory or infective disease; treatment for anaemia within the past 3 months; cirrhosis or chronic hepatitis.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Postprandial metabolic dysfunction measured by peripheral biological markers of oxidative stress and glycaemic parameters.[At 0 time and every 30 minutes to 120 minutes postprandially.]
- Secondary Outcome Measures
Name Time Method Postprandial immune dysfunction measured by peripheral biological markers of inflammation.[At 0 time and every 30 minutes to 120 minutes postprandially.]