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Analgesic efficacy of Nefopam in cancer pain: A randomized controlled study

Phase 3
Completed
Conditions
Cancer pain
cancer pain
nefopam
efficacy
Registration Number
TCTR20181016001
Lead Sponsor
Ramathibodi hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
40
Inclusion Criteria

1. Patients aged 18-80 years
2. Patients who has moderate to severe cancer pain (numeric rating scale 4/10-10/10) who needs analgesics to control pain
3. Patients who is willing to enroll the study

Exclusion Criteria

1. Patients who cannot evaluate their pain into numeric rating scale
2. Patients who are not able to use IV-PCA machine
3. Patients who are allergic to intravenous morphine
4. Patients who are on chemotherapy or radiation therapy during study period
5. Patients who undergo an operation within one week
6. Patients with a history of convulsive disorder
7. Patients who are diagnosed ischemic heart disease
8. Patients who are taking MAOI within 30 days before study period
9. Pregnants or breast feeing patients
10. Patients who deny to enroll the study

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Analgesic efficacy record data every 4 hours until completing 48 hours numeric rating scale and dose of opioids used
Secondary Outcome Measures
NameTimeMethod
Incidence of side effects from nefopam during 48 hours after starting intervention record incidence of side effects
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