To determine the ideal maintenance fluid for critically ill children.
Active, not recruiting
- Conditions
- Abnormal level of blood mineral,
- Registration Number
- CTRI/2019/10/021791
- Lead Sponsor
- Department of Pediatrics
- Brief Summary
Hospital acquired acute Hyponatremia is increasingly recognised as the cause of morbidity and mortality in children. It has been attributed primarily to the use of hypotonic intravenous fluids to maintain fluid an electrolyte balance. The use of isotonic fluid (0.9% Normal Saline with 5% Dextrose) is recommended in most circumstances. Hypotonic intravenous fluids containing less than or equal to 0.45% NaCL shouldn’t be used to provide as a routine iv fluid maintenance requirement.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Closed to Recruitment of Participants
- Sex
- All
- Target Recruitment
- 162
Inclusion Criteria
All the children more than 3 months and less than 12 years of age requiring fluid management.
Exclusion Criteria
- a) Children with age less than 3 months of age and more than 12 years of age.
- b ) Children who have received more than 72 hours of intravenous fluid.
- d) Children with Renal Disease ( AKI), Cardiac disease ( CHF) or Pituitary dysfunction , Diabetes mellitus.
- e) Children with baseline sodium values, < 130 meq/dl and > 145 meq/dl.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Proportion of subjects developing hyponatremia after receiving designated fluid for the specified time. 72 hours
- Secondary Outcome Measures
Name Time Method 1. Change in serum sodium levels from the baseline at 48,72 hours in whom iv fluids are continued. 2. Occurence of hyponatremia and hypernatremia.
Trial Locations
- Locations (1)
Lok Nayak Hospitals
🇮🇳Central, DELHI, India
Lok Nayak Hospitals🇮🇳Central, DELHI, IndiaKumar RatnjeetPrincipal investigator07838695570krat240@gmail.com