Evaluation of Perioperative Fluid Responsiveness in Neurosurgery: Interest of the Pleth Variability Index
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 70
- 试验地点
- 1
- 主要终点
- Value of PVI in fluid responsiveness in neurosurgery
研究概览
简要总结
This clinical trial aims to study the interest of the Pleth Variability Index (PVI) to evaluate perioperative fluid responsiveness in neurosurgery in adults.
The main question it aims to answer is:
• Does the Pleth variability index predict fluid responsiveness in neurosurgery? Researchers will compare the Pleth variability index to dela PP to see if it predicts fluid responsiveness in neurosurgery.
Once participants give their consent, they will be randomly assigned to one of two groups. In one group, fluid responsiveness will be monitored using the Pleth Variability Index, while in the other group, it will be monitored using delta PP.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients proposed for intracranial surgery
- •Must be aged 18 and over
- •Must be classified as ASA I, ASA II, and ASA III according to the American Society of Anesthesiologists classification
排除标准
- •Non-consenting patients
- •Patients classified ASA IV or higher
- •Cardiac arrhythmia
- •Heart disease with left ventricular ejection fraction less than 45%
- •Obesity with a BMI greater than 40 Kg/m
- •Peripheral vascular disease
- •Severe lung disease
- •End-stage renal disease
- •Intraoperative cardiac arrhythmia
- •The occurrence of cardiac arrest
- •The occurrence of hemorrhagic shock
- •Intraoperative use of low tidal volumes or high respiratory rates.
结局指标
主要结局
Value of PVI in fluid responsiveness in neurosurgery
时间窗: chanfe of PVI value from baseline to a value more than 14% and untill the end of surgery
Investigate the value of the plethysmographic variability index (PVI) in assessing the response to perioperative vascular filling in neurosurgery.
次要结局
- Amount of fluids administered intraoperatively(during the surgery)
- Renal, metabolic and hydroelectrolytic repercussions.(up to the first 24 hours postoperatively)
- Length of postoperative stay(up to hospital discharge, an average of 4 days)
- Incidence of post-operative complications(up to hospital discharge, an average of 4 days)
研究者
Hammami Rabeb
university hospital assistant
National Institute of Neurology, Tunisia