Effect of sprint training on health outcomes in individuals with obesity

Not Applicable

Recruiting

• Conditions: Metabolic and Endocrine - Normal metabolism and endocrine development and function; Obesity; Diet and Nutrition - Obesity

• Registration Number: ACTRN12621000536864
• Lead Sponsor: Prof. H. ZOUHA

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-05-06
• Last Update Posted: 10 May 2021

Recruitment & Eligibility

• Status: Recruiting
• Sex: Male
• Target Recruitment: 40

Inclusion Criteria

Sedentary males
- Age between 18 and 40 years old
- Body mass index (BMI) > 30 kg.m-2
- metabolically healthy

Exclusion Criteria

Participants were required to be
- sedentary (exercising less than 30 min/week) and nonsmokers
- moderate to no consumption of alcohol and caffeine.
- After a medical screening, none of them had identified cardiomyopathy, endocrine disorders, or orthopedic problems that would limit their participation in the training program.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
- Gut hormones (blood analysis): ghrelin, glucagon-like peptide 1, peptide YY, pancreatic<br>polypeptide, cholecystokinin, and leptin.<br><br>[Baseline, 6 weeks (primary timepoint) and 12 weeks after intervention commencement];-Inflammation (blood analysis): interleukin-1 (IL-1), IL-6 and tumour necrosis factor-alpha (TNF-a), resistin, vaspin, omentin-1, RBP-4, apelin, visfatin and MCP-1[Baseline, 6 weeks (primary timepoint) and 12 weeks after intervention commencement];- Oxydative stress (blood analysis): CAT catalase, GPx glutathione peroxidase, GSH glutathione, LPx lipid peroxidation, MDA malondialdehyde, MPO myeloperoxidase, pCarb protein carbonyl, POVPC/PGPC 1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine, SOD1/SOD2 superoxide dismutase, TBARS thiobarbituric acid-reactive substances, TEAC trolox equivalentantioxidant capacity, [Baseline, 6 weeks (primary timepoint) and 12 weeks after intervention commencement]

Secondary Outcome Measures

Name	Time	Method
Changes in body fat percentage (DEXA)[Baseline, 6 weeks and 12 weeks after intervention commencement]