Cardiac Anesthesia Registry Including Biosignal Database for Prognostication of Postoperative Renal Outcome: Cardiac Anesthesia Renal Outcome in Severance Cardiovascular Hospital - DataBase (CARS-DB)
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 10,000
- 试验地点
- 1
- 主要终点
- post-operative AKI incidence within 1 week after cardiac surgery with CPB
研究概览
简要总结
AKI(Acute Kidney Injury) is a common complication after cardiac surgery which is associated with increased mortality and morbidity. Collecting perioperative biosignal data and studying their association with renal outcomes can help improve kidney injury, mortality, and morbidity in cardiac surgical patients. Furthermore, the occurrence of AKI, length of hospital stay, and recovery of renal function after discharge are closely associated with the development of chronic kidney disease (CKD). Therefore, regular monitoring of renal function and related indicators in cardiac surgical patients can help improve long-term outcomes.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 19 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Aged 19 years and older scheduled for cardiac surgery using CPB
排除标准
- •emergency operation, the patient is foreigner or illiterate and unable to read the consent form
结局指标
主要结局
post-operative AKI incidence within 1 week after cardiac surgery with CPB
时间窗: within first 7 days after surgery
The definition of AKI refers to Kidney Disease: Improving Global Outcomes (KDIGO) Acute Kidney Injury Work Group. KDIGO Clinical Practice Guideline for Acute Kidney Injury.
次要结局
- MAKE 30 (Major adverse kidney event within 30 days)(within 30 days after surgery)
- incidence of CKD (chronic kidney disease) within 1 year(within 1 year after surgery)
- MAKE 90 (Major Adverse kidney event within 90 days)(within 90 days after surgery)
- 1 year mortality(within 1 year after surgery)
- in-hospital mortality(from day of hospitalization for surgery until discharge after surgery 1year)