International Reveiw Board of Gachon Univerity Gil Hospital
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- cerebral ischemia
研究概览
简要总结
The investigators hypothesized that positive end expiratory pressure (PEEP) would increase the regional oxygen saturation (rSO2).
详细描述
The investigators hypothesized that PEEP would increase the rSO2 during laparoscopic surgery by improving oxygenation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 20 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •ASA PS I or II adult patient undergoing laparoscopic low anterior resection with Trendelenburg position
排除标准
- •Patients with history of cerebrovascular disease, coronary occlusive disease and/or obesity (body mass index > 30) were excluded from this study.
研究组 & 干预措施
zero end-expiratory pressure
not applying PEEP during operation just applying TV=IBW*6-8ml IBW = (male; 50+0.91[(Ht-cm)-152.4], female; 45.5 +0.91[(Ht-cm)-152.4], RR 8-12/min,
干预措施: positive end expiratory pressure (Procedure)
positive end expiratory pressure
applying PEEP 10cmH2O during operation just applying TV=IBW*6-8ml IBW = (male; 50+0.91[(Ht-cm)-152.4], female; 45.5 +0.91[(Ht-cm)-152.4], RR 8-12/min,
干预措施: zero end-expiratory pressure (Procedure)
结局指标
主要结局
cerebral ischemia
时间窗: change from baseline in rSO2 at every events
induction 10 min, Pneumoperitoneum 20 min, after PEEP apply 40 min, time of operation ending cerebral oxymetry, cerebral perfusion pressure record
次要结局
未报告次要终点
研究者
Youn Yi Jo
Assistant professor
Gachon University Gil Medical Center