Intra- Versus Extraarticular Injection of Ropivacaine in Total Knee Arthroplasty

Phase 4

• Conditions: Pain, Postoperative
• Interventions: Drug: intraarticular injection with ropivacaine; Drug: extraarticular injection with ropivacaine

• Registration Number: NCT00632580
• Lead Sponsor: Hvidovre University Hospital

Brief Summary

The purpose of this study is to evaluate the optimal site for application of local anesthetics in total knee arthroplasty surgery. The hypothesis is, that improved pain relief is obtained when administering local anesthetics in the tissues sourrounding the knee joint compared to the knee joint itself.

Detailed Description

Not available

Study Timeline

• Study Start: 2008-01
• Study First Submitted: 2008-02-28
• Study First Submitted QC: 2008-02-28
• Study First Posted: 2008-03-10
• Primary Completion: 2008-07
• Study Completion: 2008-07
• Status Verified: 2009-03
• Last Update Submitted: 2009-03-17
• Last Update Posted: 2009-03-18

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• eligible for elective total knee arthroplasty
• able to speak and understand Danish
• able to give informed consent

Exclusion Criteria

• alocohol or medical abuse
• allergies to local anesthetics
• age < 18 yrs.
• intolerance to opioids

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
1	intraarticular injection with ropivacaine	intraarticular injection with local anesthetic
2	extraarticular injection with ropivacaine	intracapsular injection with local anesthetic

Primary Outcome Measures

Name	Time	Method
pain	48 hours

Trial Locations

Locations (1)

Hvidovre University Hospital; 🇩🇰 Copenhagen, Denmark