Effect of dexmedetomidine on anaesthesia requirement using computerised anaesthesia delivery system
Not Applicable
- Conditions
- Health Condition 1: null- Undergoing laparoscopic or robotic surgery
- Registration Number
- CTRI/2016/01/006483
- Lead Sponsor
- Sir Ganga Ram Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 80
Inclusion Criteria
1. ASA physical status I/II
2. Undergoing laparoscopic / robotic surgery of more than 60-minutes duration
Exclusion Criteria
1.Cardiovascular disorders (uncontrolled hypertension, Atrio-ventricular block, sinus bradycardia, congenital heart disease, reduced LV compliance & diastolic dysfunction)
2.Neurological disorders (previous neurosurgery, psychiatric disorders, autonomic nervous system disorders- orthostatic hypotension, transient ischemic attacks)
3.Any hepato-renal insufficiency
4.Uncontrolled diabetes mellitus
5.Known allergy/hypersensitivity to study drug
6.Pulmonary dysfunction (restrictive /obstructive lung disease)
7.Acute/chronic drug dependence/substance abuse
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.To analyze quantitative reduction of propofol requirements with addition of dexmedetomidine to achieve a controlled GA state. <br/ ><br>2.To assess the quality of anesthesia-depth adequacy with dexmedetomidine-propofol combination <br/ ><br>Timepoint: From beginning of anaesthesia administration till end of anaesthesia administration
- Secondary Outcome Measures
Name Time Method 1.The impact of dexmedetomidine use on intraoperative haemodynamics and postoperative analgesia. <br/ ><br>2.Assessment of any extraordinary/overriding issues with the use of dexmedetomidine as a co-anesthetic agent (e.g. haemodynamic depression, postoperative sedation, PONV) <br/ ><br>3.Postoperative sedation <br/ ><br>4.Intraoperative awareness <br/ ><br>Timepoint: From the end of anaesthesia till 48 hours postoperatively