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Early recognition and optimal treatment of acute confusion in patients with advanced cancer.

Conditions
Delirium in patients with advanced cancer
Therapeutic area: Psychiatry and Psychology [F] - Mental Disorders [F03]
Registration Number
EUCTR2009-013403-55-NL
Lead Sponsor
VU university medical center
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Authorised-recruitment may be ongoing or finished
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

• Patient has been diagnosed with advanced cancer;
• Age = 18;
• Patient or his / her significant other speaks Dutch fluently.

Are the trial subjects under 18? no
Number of subjects for this age range: 0
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 100
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range 100

Exclusion Criteria

• Delirium is due to alcohol withdrawal;
• Patient has been diagnosed with glaucoma, Parkinson’s disease or dementia;
• Patient is being treated with other neuroleptic medication or lithium (except for low dose neuroleptics used in the treatment of neuropathic pain;
• Patient has another psychiatric disorder that is considered (by investigator) to interfere withassessment of delirium;
• Patient had a QTc-interval of > 480 msec on ECG made on admission;
• Patient has a history of neuroleptic malignant syndrome;
• Patient has a history of convulsions.

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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