Establishment of in vitro testicular tissue cultuure
Not Applicable
Recruiting
- Conditions
- azoospermia
- Registration Number
- JPRN-UMIN000037701
- Lead Sponsor
- International University of Health and Welfare School of Medicine Department of Obstetrics and Gynecology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Male
- Target Recruitment
- 40
Inclusion Criteria
Not provided
Exclusion Criteria
1. Patients who can not obtain agreement to participate this study. 2. Patients who judged to be inappropriate for this study by attending doctors.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method We perform different methods of in vitro culture of human testicular tissue up to 75 days. After culture, we examine the formation of sperm by histological and molecular analyses.
- Secondary Outcome Measures
Name Time Method We evaluate the normality of different developmental stages of germ line cells by morphological and molecular analyses. Also, we explore the causes of spermatogenesis dysfunction using molecular approaches.