Effects of Letrozole compared with Danazole on patients with confirmed endometriosis: A randomized clinical trial
Not Applicable
- Conditions
- Endometriosis.Endometriosis
- Registration Number
- IRCT138812043414N1
- Lead Sponsor
- Medical University of Isfahan
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 105
Inclusion Criteria
Inclusion criteria were: women in reproductive age with regular menstruation cycles (18 to 45 days), confirmed endometriosis in laparoscopy, chronic pelvic pain and dysmenorrhoea for at least 2 weeks in each month during past 3 months. Exclusion criteria were: abnormal vaginal bleeding with unknown cause, ovarian cyst >2cm, hormone therapy during past 3 months, osteopenia, smoking, hypersensitivity to danazole and letrozole, history of convulsion, pulmonary, cardiac, hepatic or renal diseases, cerebrovascular disease and pregnancy
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Recurrence of endometriosis. Timepoint: Every month. Method of measurement: VAS.
- Secondary Outcome Measures
Name Time Method Dysmenorhea. Timepoint: every month. Method of measurement: VAS and pelvic examination.;Pelvic pain. Timepoint: every month. Method of measurement: VAS and pelvic examination.;Dysparonia. Timepoint: every month. Method of measurement: VAS and pelvic examination.