The Effect of Menstrual Cycle Phase and Protein Dose on Muscle Protein Synthesis in Response to Exercise in Young Females

University of Exeter1 site in 1 country28 target enrollmentJanuary 16, 2022

ConditionsMuscle Protein Synthesis

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Muscle Protein Synthesis
Sponsor: University of Exeter
Enrollment: 28
Locations: 1
Primary Endpoint: Muscle protein synthesis
Status: Completed
Last Updated: last year

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Adaptation to resistance exercise requires maximal rates of muscle protein synthesis, which can be achieved with post-exercise ingestion of ~20g of protein. These recommendations are based on studies in males and responses in females may vary.

Muscle recovery is related to the ability to build new muscle protein from amino acids (muscle protein synthesis). This response is thought to be impacted in females by hormones that fluctuate across different phases of the menstrual cycle. However, the effect of menstrual cycle phase on muscle protein synthesis is not known.

Registry

clinicaltrials.gov

Start Date

January 16, 2022

End Date

March 31, 2023

Last Updated

last year

Study Type

Interventional

Study Design

Parallel

Sex

Female

Investigators

Sponsor

University of Exeter

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•BMI between 18 and 30
•Recreationally active
•Regular menstrual cycle

Exclusion Criteria

•Metabolic disease
•Any motor disorder
•Use of over-the-counter pharmaceuticals, during the study.
•Pomegranate, milk or lidocaine allergy
•Taken contraceptives in the past 3 months
•Irregular menstrual cycle (less than 9 cycles per year and a length not between 21-35 days)
•Post-menopausal women
•Pregnancy and lactation