Different Menstrual Cycle in Eating Behavior Following Resistance Exercise

Not Applicable

Completed

• Conditions: Food Reward; Energy Balance; Appetitive Behavior; Menstruation
• Interventions: Other: Resistance exercise

• Registration Number: NCT06208475
• Lead Sponsor: National Taiwan Normal University

Brief Summary

The study aims to provide insights into how menstrual cycle phases impact appetite responses to resistance exercise in young women. Healthy young women will participate in four trials: the exercise session in the follicular phase, the exercise session in the luteal phase, the control session in the follicular phase, and the control session in the luteal phase. Various measurements will be taken, including subjective appetite perceptions, appetite hormones, food preferences, lactate levels, estradiol levels, progesterone levels, and energy intake.

Detailed Description

Not available

Study Timeline

• Study Start: 2023-08-01
• Study First Submitted: 2024-01-04
• Study First Submitted QC: 2024-01-15
• Study First Posted: 2024-01-17
• Status Verified: 2024-06
• Primary Completion: 2024-06-06
• Study Completion: 2024-06-06
• Last Update Submitted: 2024-06-06
• Last Update Posted: 2024-06-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 18

Inclusion Criteria

• Age: 20-30
• Healthy female with normal menstruation
• Weight stable for at least 6 months

Exclusion Criteria

• Overweight (BMI > 30 kg/m^2 or body fat > 30%)
• Hypertension (> 140/90 mmHg)
• Cardiovascular disease, cancer or other chronic diseases

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
The exercise in the luteal phase (EL)	Resistance exercise	Resistance exercise during the mid-luteal phase (approximately during days 18-25 of the menstrual cycle).
The exercise in the follicular phase (EF)	Resistance exercise	Resistance exercise during the early-follicular phase (approximately during days 1-7 of the menstrual cycle).

Primary Outcome Measures

Name	Time	Method
Change in active-GLP-1	4 hours during each study intervention	active-GLP-1 in pg/mL
Change in total-Ghrelin	4 hours during each study intervention	total-Ghrelin in pg/mL
Change in acyl-Ghrelin	4 hours during each study intervention	acyl-Ghrelin in pg/mL
Change in PYY	4 hours during each study intervention	PYY in pg/mL
Change in lactate	4 hours during each study intervention	insulin in mmol/L
Subjective appetite	4 hours during each study intervention	The appetite perceptions are obtained through a 0-100 mm visual analog scale. The variables assessed include perceptions of hunger (i.e., "How hungry do you feel?"), satisfaction (i.e., "How satisfied do you feel?"), fullness (i.e., "How full do you feel?"), prospective food consumption (i.e., "How much do you think you can eat?"), and nausea (i.e., "How nauseous do you feel?"), with 0 indicating "not at all" and 100 signifying "extremely.".
Change in total-GLP-1	4 hours during each study intervention	total-GLP-1 in pg/mL

Secondary Outcome Measures

Name	Time	Method
Change in glucose	4 hours during each study intervention	glucose in mg/dL
Explicit wanting	4 hours during each study intervention	A visual analog scale ranging from 0 to 100 mm is utilized to evaluate the question, "How much do you want some of this food now?" with 0 indicating "not at all" and 100 signifying "extremely."
Relative preference	4 hours during each study intervention	Participants are given a set of food image pairs and are asked to select their preference by answering the question, "Which food do you desire the most at the moment?". The relative preference is the sum of the times each type of food is chosen, with a maximum value of 48 and a minimum value of 0.
Fat appeal bias	4 hours during each study intervention	Fat preference (high or low) is calculated by subtracting the mean low-fat scores from the mean high-fat scores. Positive values suggest a preference for high-fat foods, while negative scores indicate a preference for low-fat or savory foods, and a score of 0 signifies an equal preference between fat content.
Energy intake	3 days during each study intervention	Participants will be required to record their diet for the day before, the current day, and the day following the experiment.
Change in TG	4 hours during each study intervention	TG in mg/dL
Change in insulin	4 hours during each study intervention	insulin in mU/L
Sex hormones	4 hours during each study intervention	Sex hormones will be measured, such as estrogen and progesterone
Explicit liking	4 hours during each study intervention	A visual analog scale ranging from 0 to 100 mm is utilized to evaluate the question, "How pleasant would it be to taste some of this food now?" with 0 indicating "not at all" and 100 signifying "extremely."
Implicit wanting	4 hours during each study intervention	Participants are given a set of food image pairs and are asked to select their preference by answering the question, "Which food do you desire the most at the moment?". The implicit wanting calculation involves further consideration of response time data based on preference choices using a standardized equation.
Taste appeal bias	4 hours during each study intervention	Taste preference (savoury or sweet) is calculated by subtracting the mean savory scores from the mean sweet scores. Positive values suggest a preference for sweet foods, while negative scores indicate a preference for savory foods, and a score of 0 signifies an equal preference between taste categories.

Trial Locations

Locations (1)

National Taiwan Normal University; 🇨🇳 Taipei, Taiwan