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Clinical Trials/NL-OMON42617
NL-OMON42617
Completed
Not Applicable

the influence of remote ischemic preconditioning on inflammation during human endotoxemia, a pilot proof-of-principle study - RISPENDO

Intensive Care0 sites30 target enrollmentTBD
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Conditionsauto-immune diseasesinfectious diseases1000381610002252

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
auto-immune diseases
Sponsor
Intensive Care
Enrollment
30
Status
Completed
Last Updated
2 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
2 years ago
Study Type
Interventional

Investigators

Sponsor
Intensive Care

Eligibility Criteria

Inclusion Criteria

  • •Age \*18 and \*35 yrs

Exclusion Criteria

  • •Use of any medication
  • •Use of recreational drugs within 21 days prior to endotoxemia experiment day
  • •Use of caffeine or alcohol within 1 day prior to endotoxemia experiment day
  • •Previous participation in a trial where LPS was administered
  • •Surgery or trauma with significant blood loss or blood donation within 3 months prior to endotoxemia experiment day
  • •Participation in another clinical trial within 3 months prior to endotoxemia experiment day
  • •History, signs, or symptoms of cardiovascular disease
  • •History of frequent vaso\-vagal collapse or of orthostatic hypotension
  • •History of atrial or ventricular arrhythmia
  • •Hypertension (RR systolic\>160 or RR diastolic\>90\)

Outcomes

Primary Outcomes

Not specified

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