Effect of Remote Ischemic Preconditioning in treatment of burns
Not Applicable
- Conditions
- Burn.Burn and corrosion of head, face, and neck
- Registration Number
- IRCT20210524051384N5
- Lead Sponsor
- Rasht University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 32
Inclusion Criteria
Age between 18 to 65 years
Acute burn injury within 24 hours
20 to 50 percent TBSA (total body surface area)
Patient classified as class 1 ASA (American Society of Anesthesiologists) : Normal healthy person
Signed informed consent
Exclusion Criteria
Severe hypertension = BP (Blood pressure) =160/90 mmHg
Ischemic changes in ECG (Electrocardiogram)
Pregnant women
Peripheral vascular diseases
Inhalation injury
Burn shock: decreased CO (Cardiac output), increased systemic vascular resistance, hypovolemia and hypoperfusion induced by severe burn injury
Patients with burn injury in both upper limbs in which the procedure couldn't be performed
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Graft to TBSA (total body surface area) percent ratio. Timepoint: At the admission. Method of measurement: Measurements based on Wallace criteria.;Total fluid requirement. Timepoint: At discharge. Method of measurement: Based on patients' files.;Hospital stay. Timepoint: At discharge. Method of measurement: Based on patients' files.;Final clinical outcome. Timepoint: At discharge. Method of measurement: Based on patients' files.
- Secondary Outcome Measures
Name Time Method Infection. Timepoint: Day 1, 3, 7, 14 and 28 post admission. Method of measurement: Based on examination done by evaluators.;Itching. Timepoint: Day 1, 3, 7, 14 and 28 post admission. Method of measurement: Asking patients.;Burning. Timepoint: Day 1, 3, 7, 14 and 28 post admission. Method of measurement: Asking patients.;Shock index. Timepoint: Hour 1, 6, 12, 24 post admission. Method of measurement: Heartbeat per minute / systolic Blood pressure in mmHg.;SIRS (Systemic inflammatory response syndrome). Timepoint: Day 1, 3, 7, 14 and 28 ?post admission. Method of measurement: Based on body temperature, heart rate, respiratory rate, and WBC (white blood cells) count.;Cr (creatinine). Timepoint: Day 1, 3, 7, 14 and 28 ?post admission. Method of measurement: Based on patients' laboratory results.