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Fluid Responsiveness in Posterior Fossa Tumor Resection: PPV and CVP Guidance

Not Applicable
Active, not recruiting
Conditions
Posterior Fossa Tumor
Brain Tumor Adult
Registration Number
NCT06595667
Lead Sponsor
Chiang Mai University
Brief Summary

To answer the question: What are the differences in intraoperative fluid administration volumes between PPV and CVP-guided strategies during posterior fossa tumor resection in the park bench position?

Detailed Description

Prospective RCT is conducted to compared the amount of fluid volume in adult patients undergoing posterior fossa surgery in park bench position.

Recruitment & Eligibility

Status
ACTIVE_NOT_RECRUITING
Sex
All
Target Recruitment
50
Inclusion Criteria
  1. Adult patients aged 18 years and above
  2. American Society of Anesthesiologists (ASA) I and II
  3. Diagnosis of posterior fossa tumor requiring surgical resection in the park bench position, under general anesthesia at our hospital
  4. Willing to participate in the study
Exclusion Criteria
  1. Arrhythmia
  2. Significant cardiac diseases
  3. Chronic obstructive airway disease
  4. Elevated intra-abdominal pressure
  5. Tumors prone to precipitate diabetes insipidus
  6. Peripheral vascular disease
  7. Pulmonary hypertension
  8. Patients in sepsis

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Total intraoperative fluid administration volumes during surgeryduring surgery

fluid and blood and blood volume transfusion during surgery

Secondary Outcome Measures
NameTimeMethod
vital signsduring the admission in neurosurgical ICU up to 3 days after surgery

blood pressure both systolic and diastolic pressure

time to extubation48 hours after surgery at the neurosurgical intensive care unit

to be able to succesfully extubated, count time period of using ventilator

Trial Locations

Locations (1)

Chiang Mai University

🇹🇭

Chiang Mai, Thailand

Chiang Mai University
🇹🇭Chiang Mai, Thailand

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