Characterization of Post Coronary Artery Bypass Grafting Atrial Fibrillation Patterns – Atrial Pathophysiology Substudy

• Conditions: I48.0; Paroxysmal atrial fibrillation

• Registration Number: DRKS00025562
• Lead Sponsor: Klinikum der Universität München, Campus Großhadern

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-06-10
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 59

Inclusion Criteria

1. Three vessel coronary artery disease or left mainstem disease
2. = 2 coronary artery bypass grafts performed
3. Preoperative left ventricular ejection fraction = 35 %
4. Preoperative sinus rhythm
5. Age > 18 years

Exclusion Criteria

1. Any history of atrial fibrillation, atrial flutter or atrial tachycardia
2. Any history of the following complex rhythm disorders:
I. Sinoatrial block
II. Sick sinus syndrome
III. Atrioventricular block > Grade 1
IV. AV node reentry tachycardia
V. AV reentry tachycardia
VI. Focal atrial tachycardia
VII. Accelerated junctional rhythm
VIII. Ventricular tachycardia
IX. Ventricular fibrillation
X. Long-QT syndrome
3. Valvular heart disease
4. Concurrent cardiac surgery (valve surgery, aortic surgery, surgical ablation)
5. Pre- or postoperative mechanical circulatory support (failure to wean from
cardiopulmonary
bypass machine / intraaortic balloon pump / extracorporeal membrane
oxygenation /
Impella® device)
6. Repeat cardiac surgery
7. LVEF < 35 %
8. Age = 18 years
9. Life expectancy < 1 year
10. Doubtful patient compliance

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
o primary outcome. Aim of the study: to further the understanding of the atrial pathophysiology of atrial fibrillation after CABG.

Secondary Outcome Measures

Name	Time	Method
See primary outcome.