Spinal Anesthesia Versus Combined Sciatic-femoral Nerve Block for Outpatient Knee Arthroscopy

Phase 4

Completed

• Conditions: Knee Arthritis
• Interventions: Drug: prilocaine; Drug: mepivacaine; Procedure: Spinal anesthesia; Procedure: Sciatic-femoral Nerve Block; Device: Sonoplex, Pajunk

• Registration Number: NCT02384915
• Lead Sponsor: ASST Gaetano Pini-CTO

Brief Summary

The aim of the study is to compare the time of home discharge in day-case patients receiving either a spinal anesthesia or a combined sciatic-femoral nerve block for knee arthroscopy

Detailed Description

Two groups: the first receive a spinal anesthesia injecting 2% hyperbaric prilocaine 40 mg with the patients in lateral decubitus and the surgical limb declive, the second a combined ultrasound-guided sciatic-femoral nerve block injecting 25 ml of 2% mepivacaine solution.

Onset time, performance time, duration of the block, time of voiding, as well as the time of home discharge will be evaluated.

Study Timeline

• Study Start: 2015-01
• Study First Submitted: 2015-02-20
• Status Verified: 2015-03
• Study First Submitted QC: 2015-03-04
• Study First Posted: 2015-03-10
• Primary Completion: 2015-05
• Study Completion: 2015-05
• Last Update Submitted: 2015-05-07
• Last Update Posted: 2015-05-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• outpatients knee arthroscopy

Exclusion Criteria

• diabetes
• allergy to local anesthetic
• patient refusal
• chronic opiods assumption

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Spinal anesthesia	Spinal anesthesia	Intrathecal injection of 2 ml (40 mg) of 2% hyperbaric prilocaine at L3-L4 interspaces through a 100mm Sprotte 25 G spinal needle (Pencan, b-brawn, Germay) in lateral decubitus position, (with limb to operate declive).
peripheral nerve block	Sonoplex, Pajunk	Ultrasound-guided sciatic-femoral nerve block injecting 25 ml of a 2% mepivacaine solution,15 ml on femoral nerve and 10 ml on sciatic nerve through a 80 mm 22g eco-reflex needle (Sonoplex, Pajunk, Germany)
peripheral nerve block	Sciatic-femoral Nerve Block	Ultrasound-guided sciatic-femoral nerve block injecting 25 ml of a 2% mepivacaine solution,15 ml on femoral nerve and 10 ml on sciatic nerve through a 80 mm 22g eco-reflex needle (Sonoplex, Pajunk, Germany)
Spinal anesthesia	prilocaine	Intrathecal injection of 2 ml (40 mg) of 2% hyperbaric prilocaine at L3-L4 interspaces through a 100mm Sprotte 25 G spinal needle (Pencan, b-brawn, Germay) in lateral decubitus position, (with limb to operate declive).
peripheral nerve block	mepivacaine	Ultrasound-guided sciatic-femoral nerve block injecting 25 ml of a 2% mepivacaine solution,15 ml on femoral nerve and 10 ml on sciatic nerve through a 80 mm 22g eco-reflex needle (Sonoplex, Pajunk, Germany)

Primary Outcome Measures

Name	Time	Method
Time to home discharge	12 hours

Trial Locations

Locations (1)

Istituto Ortopedico G. Pini; 🇮🇹 Milan, Milano, Italy