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Clinical Trials/NCT05531396
NCT05531396
Unknown
Not Applicable

The Effects of Agility Training and Its Relations on Physical Performance, Cognitive Function and Brain Activities in Elderly

National Taiwan University Hospital0 sites30 target enrollmentSeptember 5, 2022
ConditionsElderlyHealthy

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Elderly
Sponsor
National Taiwan University Hospital
Enrollment
30
Primary Endpoint
Agility Challenge for the Elderly (ACE)
Last Updated
3 years ago

Overview

Brief Summary

Agility comprised of cognitive and physical functions, which influences whole-body movement with change of speed and direction. Agility training is widely used in athletes, and recent studies have begun to apply it into the elderly. Agility training is multidimensional and highly functional, which makes it possible to provide more efficient training in limited time. In elderly, the decrement of cognitive function, muscle strength in the upper and lower limbs, the percentage of body fat, body flexibility and endurance caused by aging will make it difficult for the elderly to perform movements. Therefore, it is essential to explore whether agility training can achieve the improvement of the physical function and cognitive function in elderly, and to find the relationship between the two functions and brain activity. Method: This study will recruit 60 participants, and randomly allocate to control group and agility training. The training groups will have 8 weeks of training, 2 times a week, 45 minutes of training each time. Assessment will be performed before and after intervention in 1-week, and with 1-month follow-up. Assessment including agility ability, physical function, cognitive function, brain activity, and functional assessment scales.

Registry
clinicaltrials.gov
Start Date
September 5, 2022
End Date
June 30, 2023
Last Updated
3 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • older than 65 years old
  • score of Mini-Mental State Examination (MMSE) ≥ 24
  • able to walk independently for more than 30 meters without assistive aids
  • able to follow orders

Exclusion Criteria

  • poorly controlled or unstable systematic disease
  • has a history of central nervous system disease
  • currently taking antidepressants, anti-anxiety, or other psychiatric drugs that may affect blood flow in the brain
  • has other medical conditions for which exercise is contraindicated; (5) subjects with achromatopsia.

Outcomes

Primary Outcomes

Agility Challenge for the Elderly (ACE)

Time Frame: Baseline, 8 weeks, and 12 weeks

An agility course developed for a 9m x 18m volleyball court and includes three segments that each aim to test a specific aspect of agility, including stop-and-go, change of direction, and spatial orientation.

Secondary Outcomes

  • Fall history and fear of falls(Baseline, 8 weeks, and 12 weeks)
  • Brain activation(Baseline, 8 weeks, and 12 weeks)
  • Quality of life (QOL)(Baseline, 8 weeks, and 12 weeks)

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