Phenotypes of Adults with Non-atopic Asthma; Mechanisms and Aetiology
Completed
- Conditions
- asthmabronchitis10006436
- Registration Number
- NL-OMON33169
- Lead Sponsor
- Medisch Centrum Leeuwarden
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 200
Inclusion Criteria
non-atopic asthma
age >= 18 yr
Exclusion Criteria
allergy
COPD without features of asthma
pregnancy
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Study 1: the 3-4 separate subtypes of non-atopic asthma as defined by unbiased<br /><br>cluster analysis.<br /><br>Study 2: The association between level of NO in exhaled air, percentage of<br /><br>eosinophils in induced sputum and extent of sinus disease as assessed by CT<br /><br>sinus score will be investigated by correlation analyses.<br /><br>Study 3: Sensitivity, specificity, positive and negative predictive value of<br /><br>the eNose in detecting sinus disease in non-atopic asthma. </p><br>
- Secondary Outcome Measures
Name Time Method <p>not applicable</p><br>