Salivary and Serum Levels of Chemerin and MMP-9 in Oral Premalignant and Malignant Lesions
Completed
- Conditions
- Oral CancerPrecancerous Conditions
- Registration Number
- NCT02323672
- Lead Sponsor
- Cairo University
- Brief Summary
45 individuals were subdivided into 3 groups, 15 patients with oral premalignant lesions, 15 patients with oral malignant lesions and 15 control individuals. Levels of chemerin and MMP-9 were evaluated in serum and saliva of these subjects utilizing the ELISA technique.
- Detailed Description
45 individuals were subdivided into 3 groups, 15 patients suffering from oral premalignant lesions, 15 patients suffering from oral malignant lesions and 15 individuals having age, gender and periodontal status matched with both patients groups acting as a control group. Serum and whole unstimulated saliva samples were collected from all the included groups in order to determine chemerin and MMP-9 in serum and saliva utilizing the ELISA technique.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 45
Inclusion Criteria
- patients with oral premalignant lesions.
- patients with oral malignant lesions.
Exclusion Criteria
- any systemic disease other than oral premalignant or malignant lesions. smokers. pregnant females. periodontal diseases.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method salivary levels of chemerin in patients with oral premalignant and malignant lesions. 1 day
- Secondary Outcome Measures
Name Time Method serum levels of chemerin in patients with oral premalignant and malignant lesions. 1 day serum levels of MMP-9 in patients with oral premalignant and malignant lesions. morning visit salivary levels of MMP-9 in patients with oral premalignant and malignant lesions. 1 day