Can transcranial direct current stimulation help attention in Lewy body dementia?

Not Applicable

Conditions: Health Condition 1: null- Dementia with Lewy bodies and Parkinsons Disease with Dementia

Registration Number: CTRI/2015/05/005751

Lead Sponsor: Institute of Neurosciences Kolkata

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Open to Recruitment

Sex: Not specified

Target Recruitment: 65

Inclusion Criteria

Participants are required to

Have been stable on anti-cholinesterase, anti-psychotic, memantine and/or anti-parkinsonian medication for at least one month prior to participation.

Be able to provide written, informed consent

Be free from concurrent major psychiatric illness (e.g. major depression).

Be free from any severe physical illness or co-morbidities which might limit their ability to fully participate in the study, or influence the effects of tDCS.

Exclusion Criteria

Participants will be unable to take part if any of the following apply:

If they have skin allergies or sensitivities to electrode gels, or any significant dermatological / scalp disease.

A history of excess alcohol intake.

A history of moderate-to-severe visual impairment secondary to glaucoma, cataract, or macular degeneration.

If they have metallic implants in the head/neck area or electronic implants of any kind (including pacemakers).

If they have a history of other neurological illness including, but not limited to stroke, intracerebral pathology and epilepsy.

If they are currently taking psychotropic or other medications which may significantly interfere with cognitive testing and tDCS efficacy (including high dose antipsychotics, dopamine agoinsts, sedative antidepressants, benzodiazepines except when low dose and used as hypnotics or treatment for REM-sleep behaviour disorder and centrally acting anticholinergic drugs).

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Four computerised attentional tasks: Simple reaction time; Choice reaction time; Digit Vigilance; Modified Attentional Network Task. <br/ ><br>Timepoint: Time 1 and Time 2 (between 24 hours and one week after Time 1) <br/ ><br>

Secondary Outcome Measures