Brain Circuitry Analysis in Bipolar Disorder
Suspended
- Conditions
- Bipolar Disorder
- Registration Number
- NCT05186077
- Lead Sponsor
- Jennifer Sweet
- Brief Summary
The goal of this cross-sectional study is to use diffusion-weighted imaging based tractography (DWT) to assess white matter (WM) pathways in treatment-refractory bipolar disorder (REF-BD) and treatment responsive bipolar disorder (RSP-BD) subjects compared to healthy controls (HCs). This project will include a prospective controlled trial to include 50 subjects with REF-BD, 50 patients RSP-BD and 50 healthy volunteers.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- SUSPENDED
- Sex
- All
- Target Recruitment
- 42
Inclusion Criteria
Not provided
Exclusion Criteria
Not provided
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Characterize white matter (WM) connectivity with DWT to identify an anatomical substrate for BD that has future potential as a therapeutic target Day 1 The imaging visit will consist of an MRI with diffusion-weighted imaging (DWI) sequences
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
University Hospitals Cleveland Medical Center
🇺🇸Cleveland, Ohio, United States
University Hospitals Cleveland Medical Center🇺🇸Cleveland, Ohio, United States