Protein requirements in healthy adult men as assessed by the Indicator Amino Acid Oxidation (IAAO) technique: a replication study
Recruiting
- Conditions
- - Protein requirements- Protein metabolism
- Registration Number
- NL-OMON26694
- Lead Sponsor
- Maastricht University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 12
Inclusion Criteria
Male
- Aged between 18-35 years
- Healthy, recreationally active (exercise at least 1 per two weeks and maximum 4 days a week)
- 18.5 = BMI = 30 kg/m2
- No physical limitations (i.e. able to perform all activities associated with daily living in an independent manner).
Exclusion Criteria
- Smoking
- Musculoskeletal disorders
- Metabolic disorders
- Use of any medications known to affect protein metabolism (i.e. corticosteroids, non-steroidal anti-inflammatories, or prescribed acne medications).
- Chronic use of gastric acid suppressing medication or anti-coagulants
- Unstable weight over the last three months
- Diagnosed GI tract disorders or diseases
- Blood donation in the past 2 months
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The estimated average protein requirement (EAR) and the recommended daily allowance (RDA) of the studied population.
- Secondary Outcome Measures
Name Time Method Carbon dioxide production, 13CO2 production, plasma and urine L-[1-13C]-phenylalanine enrichments, and plasma and urine phenylalanine concentration in a young, healthy, male population when applying the IAAO technique.