NL-OMON23555
Completed
Not Applicable
Effect of deep versus moderate neuromuscular block during sevoflurane anesthesia on intraoperative surgical conditions, hemodynamics and postoperative pain in patients undergoing laparoscopic (donor) nephrectomies
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- MC
- Enrollment
- 100
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •(i) Patients that will undergo an elective laparoscopic (donor) nephrectomy;
- •(ii) ASA class I\-III
- •(iii) \> 18 years of age;
- •(iv) Ability to give oral and written informed consent.
Exclusion Criteria
- •(i) Known or suspected neuromuscular disorders impairing neuromuscular function;
- •(ii) Allergies to muscle relaxants, anesthetics or narcotics;
- •(iii) A (family) history of malignant hyperthermia;
- •(iv) Women who are or may be pregnant or are currently breast feeding;
- •(v) Renal insufficiency, as defined by serum creatinine x 2 of normal, or urine output \< 0\.5 ml/kg/h for at least 6 h. When available, other indices will be taken into account as well such as glomerular filtration rate \< 60 ml/h and proteinuria (a ratio of 30 mg albumin to 1 g of creatinine).
- •(vi) Previous retroperitoneal surgery at the site of the current surgery.
- •(vii) Body mass index \> 35 kg/m2
Outcomes
Primary Outcomes
Not specified
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