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A randomized single-blind trial of the therapeutic effects and safety of halved dose antipsychotics for treating relapse in patients with schizophrenia receiving high dose antipsychotic therapy

Not Applicable
Conditions
schizophrenia
Registration Number
JPRN-UMIN000047785
Lead Sponsor
Showa University
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
54
Inclusion Criteria

Not provided

Exclusion Criteria

intellectual disability, neurodevelopmental disorders, organic, including symptomatic, mental disorder, long term depot antipsychotics within 3 months, electroconvulsive therapy within 6 months

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
the period from occurrence of relapse until relapse symptom improvement
Secondary Outcome Measures
NameTimeMethod
Psychiatric symptoms will be evaluated according to the Positive and Negative Syndrome Scale (PANSS), and extrapyramidal symptoms (EPS) according to the Drug-induced Extra-pyramidal Symptoms Scale (DIEPSS) at baseline, at relapse, and after remission. All adverse events that appear will be evaluated.
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