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Amino acids in type 2 diabetes

Completed
Conditions
obesitytype 2 diabetesmetabolic syndrome
Registration Number
NL-OMON20131
Lead Sponsor
Maastricht University Medical Center (MUMC+)
Brief Summary

/A

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
30
Inclusion Criteria

In order to be eligible to participate in this study, the participant must meet all of the following criteria:

-male or postmenopausal females

Exclusion Criteria

-participants will be excluded when being diagnosed with active cardiovascular disease, diabetic foot, polyneuropathy, retinopathy

-participants will be excluded when having uncontrolled hypertension

Study & Design

Study Type
Observational non invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
i) leucine oxidation rate (umol kg-1 min-1)<br>ii) insulin sensitivity (umol kg-1 min-1)<br>
Secondary Outcome Measures
NameTimeMethod
i) mitochondrial function (O2-flux pmol mg-1 s-1)<br>ii) fat accumulation in the liver (%)
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