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Clinical Trials/NCT01304212
NCT01304212
Completed
Phase 4

Comparison of the Analgesic Effect of Femoral Nerve Block, Intraarticular Infiltration or a Combination of Both in the Control of Pain in Total Knee Arthroplasty

Jose Antonio Bernia Gil1 site in 1 country137 target enrollmentApril 2011

Overview

Phase
Phase 4
Intervention
ropivacaine
Conditions
Pain
Sponsor
Jose Antonio Bernia Gil
Enrollment
137
Locations
1
Primary Endpoint
postoperative pain
Status
Completed
Last Updated
11 years ago

Overview

Brief Summary

The purpose of this study is to compare the analgesic effectiveness of three techniques: the femoral nerve block, intraarticular infiltration or a combination of both in the control of pain in total knee arthroplasty (KA). The hypothesis to be tested in this study is that the performance multimodal postoperative pain KA combining two analgesic techniques to obtain better analgesia than when applied separately.

Registry
clinicaltrials.gov
Start Date
April 2011
End Date
February 2014
Last Updated
11 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Jose Antonio Bernia Gil
Responsible Party
Sponsor Investigator
Principal Investigator

Jose Antonio Bernia Gil

PhD,MD

Consorci Sanitari de Terrassa

Eligibility Criteria

Inclusion Criteria

  • intervention program for total knee arthroplasty
  • ASA I, II, III
  • over 65 years old

Exclusion Criteria

  • ASA \> III
  • patients who refuse the realization of technical loco-regional anesthesia
  • presence of coagulopathy or impaired hemostatic function
  • BMI \> 35
  • Serious intraoperative complications
  • patients undergoing bypass and aortic-femoral or femoro popliteal bypass operated leg
  • patients treated for chronic pain diagnosed processes, different knee osteoarthritis

Arms & Interventions

femoral block

Intervention: ropivacaine

local infiltration + femoral nerve block

Combination of local infiltration with drugs and femoral nerve block

Intervention: morphine ,ketorolac

several drugs local infiltration

Intervention: ropivacaine,morphine chloride,epinephrine,ketorolac

Outcomes

Primary Outcomes

postoperative pain

Time Frame: 48 hours postoperatively

Is measured at the time of starting rehabilitation, postoperatively 48 hours using visual analog scale, numerical and categorical verbal pain scale at 12,24 and 48 hours

Study Sites (1)

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