Comparison of two methods of dose calculating of propofol for induction of general anesthesia according to either Ideal Body Weight(IBW) or Fat Free Mass(FFM), in morbid obese patient: parallel double - blinded clinical trial
Phase 3
Recruiting
- Conditions
- Morbid obese.Overweight and obesity
- Registration Number
- IRCT20201024049135N1
- Lead Sponsor
- Iran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Obesity BMI more than 35
Age 18-59 years
ASA ll and lll
Undergoing for bariatric surgery
Exclusion Criteria
Difficult airway
The need for awake intubation
Severe systemic diseases
Impaired renal and hepatic function
History of allergies to the drugs studied
Behavioral disorders and the use of psychiatric drugs
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Onset time of the dose of propofol (electroencephalographic depression) according to the study group which is determined by a decrease in bispectral index to less than 60. Timepoint: During induction of general anesthesia. Method of measurement: evaluated by bispectral index recording.
- Secondary Outcome Measures
Name Time Method Evaluation of the extent of decrease in mean arterial pressure. Timepoint: During induction of anesthesia and every 3 minutes. Method of measurement: Through noninvasive blood pressure monitoring.;Measure the maximum depth of anesthesia. Timepoint: During induction of anesthesia and every 3 minutes. Method of measurement: Bispectral index Monitoring.;Evaluation of the extent of heat rate decrease during induction of anesthesia. Timepoint: Continuous monitoring. Method of measurement: Electrocardiography.