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Effects of pressure versus volume controlled mechanical ventilation on intracranial pressure and cerebral perfusion pressure – A pilot study - Vent-ICP
Klinikum Kassel, Neurologie0 个研究点目标入组 30 人开始时间: 2015年12月30日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 30
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized controlled study
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 18 Years 至 one（—）
- 性别
- All
入选标准
- •need for mechanical ventilation
- •- need for ICP monitoring
- •- written informed consent by legal proxy
排除标准
- •- assisted breathing, spontanious breathing
- •- severe respiratory failure (FiO2 <= 45%,P/F ratio < 200, PEEP > 10mmHg)
- •- elevated ICP > 25mmHg and need for ICP therapy within the last 6 hours
- •- Circulatory shock: shock index >1 (Heart frequency/ systolic blood pressure) within the last 6 hours
- •- fever: body temperature >= 38,5°C within the last 6 hours
- •- acidosis: PH < 7,35 within the last 6 hours
- •- blood glucose level < 60mg//dl or > 500mg/dl within the last 6 hours
- •- severe respiratory diseases such as lung fibrosis or COPD
- •- prone positioning
研究者
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