Evaluation and mechanism of Qinji Liangxue mixture in the treatment of hemorrhagic internal hemorrhoids based on ultrasonic elastography

Phase 1

• Conditions: Internal hemorrhoids

• Registration Number: ITMCTR2000003953
• Lead Sponsor: Shanghai Municipal Hospital of Traditional Chinese Medicine Affiliated to Shanghai University of Traditional Chinese Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1. Patients with grade I and II internal hemorrhoids met the above diagnostic criteria, and the bleeding symptoms did not exceed 7 days;
2. Aged 18 to 75 years old;
3. Hemorrhoid mucosa hyperemia, erosion or bleeding points were found under anoscopy;
4. Those who voluntarily participate in the experiment and sign the informed consent form.

Exclusion Criteria

1. Patients with anal fissure, anal fistula, inflammatory bowel disease, blood disease, diabetes, colorectal cancer and other diseases and mental diseases;
2. Pregnant or lactating women;
3. Those who have used the related drugs (including oral drugs and local drugs) for the treatment of internal hemorrhoids bleeding in recent one month;
4. Taking anticoagulant drugs, antiplatelet aggregation drugs, hormones, non steroidal analgesics and other drugs that affect the function of blood coagulation;
5. Patients with abnormal blood and urine routine, PT, APTT, AST, ALT, AKP, TBIL, BuN, SCR and ECG.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Blood and urine routine, blood coagulation (PT), activated partial thrombin time (APTT), thrombin time (TT), fibrinogen (FIB)), liver and kidney function (AST, ALT, AKP, TBIL, BuN, SCr), electrocardiogram;