Corticosteroids for the Prevention of Atrial Fibrillation After Cardiac Surgery
- Registration Number
- NCT00442494
- Lead Sponsor
- Kuopio University Hospital
- Brief Summary
Atrial fibrillation is the most common arrhythmia to occur after cardiac surgery. Inflammatory response may be one etiological factor.
We hypothesized that intravenous corticosteroid administration after cardiac surgery prevents AF after cardiac surgery.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- All
- Target Recruitment
- 1
Inclusion Criteria
- Patients scheduled to undergo their first on-pump CABG, aortic valve replacement or combined aortic valve replacement and CABG were enrolled.
Exclusion Criteria
- Previous episodes of AF or flutter
- Uncontrolled diabetes mellitus
- Systemic mycotic infection
- Active tuberculosis
- Cushing's syndrome
- Psychotic mental disorder
- Herpes Simplex keratitis
- Serum creatinine exceeding 200 µg/ml
- Patients were also excluded if they had a history of previous peptic ulcer or thrombophlebitis.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Study couldn´t start due to investigator intravenous hydrocortisone Study couldn´t start due to investigator
- Primary Outcome Measures
Name Time Method Study couldn´t start due to investigator Study couldn´t start due to investigator Study couldn´t start due to investigator
- Secondary Outcome Measures
Name Time Method Study couldn´t start due to investigator Study couldn´t start due to investigator Study couldn´t start due to investigator