The acute effects of a green tea extract, -Epigallocatechin Gallate (EGCG) on cognition, stress, brain function and cardiovascular function.

Phase 3

Completed

• Conditions: Cognitive Function; Relaxation and Stress; Cardiovascular Function; Brain Function; Alternative and Complementary Medicine - Other alternative and complementary medicine; Mental Health - Studies of normal psychology, cognitive function and behaviour; Cardiovascular - Normal development and function of the cardiovascular system

• Registration Number: ACTRN12609000646246
• Lead Sponsor: Swinburne University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2009-07-30
• Last Update Posted: 9 November 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 32

Inclusion Criteria

Healthy non smoking
- English speaking and right handed
- No history of anxiety, depression, epilepsy or psychiatric disorders
- Not taking any medications, for example anti-coagulants, anti-depressants, anti-cholinergics or acetycholinesterase inhibitors
- Not regularly taking any herbal extracts or vitamin supplements
- Not taking illicit drugs
- Possess no health conditions that would affect food metabolism including the following: food allergies, kidney disease, liver disease and/or gastrointestinal diseases (e.g Irritable bowel syndrome, celiac disease, peptic ulcers)
- Not pregnant or currently breast feeding
- Willing to participate in two 7 hour session in accordance to protocol
- Provide a signed and dated informed consent form

Exclusion Criteria

- Currently consume green tea on a daily basis
- Consume more than 3 standard alcoholic drinks per day
- Have a habitual caffeine intake exceeding 300mg (>3-4 cups of coffee per day)
- Smoker
- Have a known allergy to green tea and/or EGCG
- A history or diagnosis of hypotension, hypertension or heart disease
- A history of anxiety, depression, epilepsy or psychiatric disorders
- Currently taking any medications, herbal extracts, vitamin supplements or illicit drugs
- Any health conditions including celiac disease that would effect food metabolism including the following: food allergies, kidney disease, liver disease and/or gastrointestinal diseases (e.g. Irritable bowel syndrome, peptic ulcers)
- Pregnancy or breast feeding
- Current study participation in other trials involving investigational or marketed products

Study & Design

• Study Type: Interventional
• Study Design: Not specified