The effect of N-Acetylcystein on prevention of Acute Renal injury due to Cyclosporine Administration in patients undergoing bone marrow transplantatio

Phase 2

• Conditions: Condition 1: AML. Condition 2: ALL. Condition 3: Acute Renal injury.; Acute myeloblastic leukaemia; Acute lymphoblastic leukaemia

• Registration Number: IRCT201306031030N14
• Lead Sponsor: Hematology Oncology and SCT Research Center

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

1- Patients with acute myeloid leukemia or acute lymphocytic leukemia
2- Full match Allogeneic Bone Marrow Transplantation
3- Age between 15-60 year old
4- Treatment of Cyclosporin after transplantation

Exclusion criteria:
1- Patient under 15 year old
2- Patient with diabetes, chronic kidney disease, liver disorder or hypertension

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Serum Creatinin. Timepoint: 6 and 3 days before transplantation and 3, 9 and 5 day after transplantation. Method of measurement: Lab test.

Secondary Outcome Measures

Name	Time	Method
rine NGAL. Timepoint: 6 and 3 days before transplantation and 3, 9 and 5 day after transplantation. Method of measurement: Lab test.