Comparison of Effect of Equi-MAC Anesthetics on PSI

Not Applicable

Completed

Brief Summary: The aim of this study is to compare the patient state index values produced by equi-MAC of sevoflurane and desflurane in patients undergoing single-agent volatile anesthesia.

Detailed Description: There have been several studies comparing electroencephalogram-derived indices produced by sevoflurane and desflurane. However, to the best of our knowledge, there has been no study which compared the two inhaled anesthetics using patient state index. Therefore, the aim of this study is to compare the patient state index values produced by sevoflurane and desflurane at equi-MAC in patients undergoing single-agent inhalation anesthesia.

Recruitment & Eligibility

Inclusion Criteria

patients aged between 19 and 65 yr
patients with American Society of Anesthesiologists physical status classification I or II
patients scheduled for elective surgery under volatile anesthesia
patients obtaining written informed consent

Exclusion Criteria

patients with a history of any psychiatric or neurological disease
patients receiving any medication affecting the autonomic or central nervous system
patients with a history of alcohol or drug abuse
pregnant or lactating women

Arm && Interventions

Group	Intervention	Description
Sevoflurane	Sevoflurane	Anesthesia is maintained with sevoflurane.
Desflurane	Desflurane	Anesthesia is maintained with desflurane.

Primary Outcome Measures

Name	Time	Method
patient state index	After a 30-min waiting period from the induction of anesthesia	patient state index value at a steady-state anesthesia of equi-MAC

Secondary Outcome Measures

Name	Time	Method

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