Prediction in patients who had a stroke and needed care at an intensive care unit concerning their changes of survival and the capacity to function in daily life after their illness
Completed
- Conditions
- Strokeischaemic and intracerebral haemorrhagic cerebrovascular accident (CVA)Circulatory System
- Registration Number
- ISRCTN13328713
- Lead Sponsor
- niversity College London Hospital NHS Foundation Trust
- Brief Summary
1. 2018 results in https://www.ncbi.nlm.nih.gov/pubmed/29608513 (added 23/01/2019)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
1. Adult patients (aged 18 years or older) admitted via the Emergency Department (ED) to either the general or neurosurgical ICU of one of the University College London Hospitals (UCLH) in North Central London between February 2010 and May 2012
2. Clinical diagnosis of acute ischaemic or intracerebral haemorrhagic stroke, confirmed by non-contrast cranial CT scan
Exclusion Criteria
1. Patients with a subarachnoid or subdural bleeding
2. Patients with a known intra-cerebral or intracerebellar tumour
3. Patients who suffered an in-hospital stroke
4. Patients who were referred from another ICU for the same diagnosis
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method All-cause mortality after ischaemic or intracerebral haemorrhagic stroke. The follow-up timepoints lie between 4 and 6 years (depending on when the patient suffered a critical stroke) or on the moment the patient died.
- Secondary Outcome Measures
Name Time Method Functional outcome, measured using the modified Rankin scale at hospital discharge and at one year follow-up check appointment and recorded by the patient’s primary treating physician. The original data using this ordinal scale will be dichotomised for analysis. Good functional outcome is defined as independent functional status (mRS 0-2) versus poor functional outcome, defined as dependent functional status or dead (mRS 3-6). Furthermore, transition in mRS will be taken into account, defined as improved functional status (mRS even or increased between discharge and after one year) versus declined functional status (mRS decreased between discharge and after one year).