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HIIT for Inflammatory Rheumatic Disease: Man vs Machine

Not Applicable
Completed
Conditions
Inflammatory Rheumatism
Interventions
Behavioral: Effective endurance 4x4 training - Supervised
Device: Effective endurance 4x4 training - APP
Registration Number
NCT04649528
Lead Sponsor
Molde University College
Brief Summary

The purpose of this study is to compare two modes of delivering high-intensity interval training (HIIT) in a population with inflammatory rheumatic disease over 10 weeks. One group will recieved HIIT supervised by a healthcare professional, the other group will perform self-monitored HITT with guidance by a smarthpone application.

Detailed Description

People with inflammatory rheumatic diseases (IRS) such as rheumatoid arthritis (RA), spondyloarthritis (SpA) and systemic lupus erythematosus (SLE) have been shown to have reduced cardiovascular fitness and quality of life than the general population. Cardiovascular health is the single most important factor of total mortality. It has been shown previously that individuals with IRS tolerate both endurance training, resulting in improvement in function and cardiovascular health while also having a positive effect on disease activity measured through inflammation, pain, joint health and fatigue. In recent years, studies have also been conducted that demonstrate both the safety and effect of aerobic 4x4min high-intensity interval training (HIIT) for patients with IRS.

This study will involve an intervention period consisting of 20 HIIT sessions. Participants are randomized into one of two training groups. One group will perform HIIT under the supervision of a healthcare professional. The other group will perform the same HIIT training with identical instructions, however they will be self-monitored with the aid and guidance of a mobilephone application.

The purpose of the intervention is to increase maximum oxygen uptake and improve quality of life. The intervention period will consist of 2 weekly sessions lasting approximately 35 minutes performed on non-consecutive days. The endurance training will consist of 4 intervals of 4 minutes duration, separated by a 3-4 minute active break and follows the principle of intensive aerobic interval training. Before and after the training period, identical testing (approximately 30-40 min) will be performed by both intervention groups. The testing will include measurements of work economy and maximal oxygen uptake in an endurance test. Additionally, quality of life questionnaires will be obtained.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
49
Inclusion Criteria
  • Inflammatory rheumatic disease
Exclusion Criteria
  • Inability to complete the testing procedures
  • Pregancy
  • Not able to perform exercise intervention
  • Planed surgeries or other plans during initial exercise intervention period than directly will effect the testing or training.
  • Access to a smartphone
  • Less than 80% compliance of planned training sessions

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Supervised HIITEffective endurance 4x4 training - SupervisedExercise intervention, 20 supervised by healthcare professional
APP HIITEffective endurance 4x4 training - APPExercise intervention, 20 self-monitored assisted by a mobilephone application
Primary Outcome Measures
NameTimeMethod
Change in physiological measuresAt baseline and after 10 weeks of HIIT

Maximal oxygen uptake

Secondary Outcome Measures
NameTimeMethod
Change in health-related quality of lifeAt baseline and after 10 weeks of HIIT

Questionnaire (Norwegian RAND-36), scoring on a 0-100 scale with higher scores identifying better outcomes

Trial Locations

Locations (1)

Myworkout - Medical Rehabilitation Clinic

🇳🇴

Trondheim, Please Select, Norway

Myworkout - Medical Rehabilitation Clinic
🇳🇴Trondheim, Please Select, Norway
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