Comparison of clonidine and dexmedtomidine as additives to the routinely used drug for spinal anaesthesia: bupivacaine in pregnant females delivering by the surgical method, commonly known as Caesarean delivery.
Not Applicable
Completed
- Conditions
- Health Condition 1: O00-O9A- Pregnancy, childbirth and the puerperium
- Registration Number
- CTRI/2020/10/028490
- Lead Sponsor
- Department of Anaesthesiology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 90
Inclusion Criteria
All term ( >36 weeks) pregnant women who fall under the American Society of Anaesthesiologists (ASA) class 2, scheduled for elective caesarean section
Exclusion Criteria
1. Patientâ??s refusal to participate.
2. Gestational age less than 36 weeks.
3. Active or early labour, ruptured membranes.
4. Placenta previa.
5. Patientâ??s body mass index (BMI) >35kg/m2.
6. Hypertension or pre-eclampsia.
7. Diabetes Mellitus or Gestational Diabetes.
8. Intrauterine growth restriction.
9. Any history or clinical evidence of cardiac disease.
10. Any contraindications to regional anaesthesia, such as local infection or bleeding disorders.
11. Patients falling under ASA3 and above.
12. Coagulation abnormalities.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To evaluate the efficacy and safety of intrathecal clonidine and dexmedetomidine as adjuvants to bupivacaine for postoperative analgesia. <br/ ><br>Timepoint: Intra operative monitoring of haemodynamic parameters - every 5 minutes for the first half an hour followed by every 10 minutes till the completion of surgery.
- Secondary Outcome Measures
Name Time Method â??To compare their duration of post operative analgesia.Timepoint: Post operative monitoring every half an hour