The application of contrast-enhanced ultrasound to acute kidney injury after sepsis

Not Applicable

Completed

• Conditions: Sepsis, severe sepsis and septic shock; Infections and Infestations; Sepsis

• Registration Number: ISRCTN14728986
• Lead Sponsor: Zhejiang Provincial Natural Science Foundation of China

Brief Summary

2019 protocol in https://pubmed.ncbi.nlm.nih.gov/31362958/ (added 27/07/2020)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-01-11
• Study Completion: 2019-09-30
• Last Update Posted: 10 August 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

1. Patients with sepsis, severe sepsis and septic shock can be admitted for the enrollment if they were over 18 years old
2. Sepsis is defined as an acute change in total SOFA score = 2 points as a result of anti-inflammatory function. The definition of septic shock is sepsis with persistent hypotension, requiring vasopressors for the maintenance of mean arterial pressure (MAP) =65 mmHg and with serum lactate level > 2 mmol/L (18mg/dL), inspite of the administration of adequate volume.

Exclusion Criteria

1. EICU stay less than 24 hours or refuse related salvage treatment
2. Patients with chronic kidney disease and long-term hemodialysis
3. Critically ill patient who had already started RRT due to AKI before EICU admission
4. Past history of kidney transplantation
5. AKI caused by obstructive causes

Study & Design

• Study Type: Observational
• Study Design: Not specified