Effect of the Addition of Dexmedetomidine to Bupivacaine During Supraclavicular Brachial Plexus Blockade for Forearm Surgery.
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 44
- 试验地点
- 1
- 主要终点
- the duration of sensorial block
研究概览
简要总结
the aim of this study was effect of the addition of dexmedetomidine to bupivacaine during supraclavicular brachial plexus blockade for forearm surgery, by low doses bupivacaine providing prolonged analgesia after surgery.
详细描述
Anaesthesia for surgeries to the upper extremity commonly is provided using brachial plexus anaesthesia.Various local anaesthetic mixtures can be used to prolong local anaesthesia duration and epinephrine , opioids and dexmedetomidine are frequently used for this purpose. this study was conducted to compare the effects of adding dexmedetomidine to local anaesthetics in the supraclavicular brachial plexus block by using nerve stimulators and ultrasonography guided. dexmedetomidine has also been found the prolong the duration of bupivacaine infraclavicular brachial plexus block.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •18-65 age
- •unwanted general anaesthesia
- •single forearm, arm surgery
排除标准
- •major psychiatric problems
- •major neurologic deficits
- •coagulopathy
- •drug allergies
- •chronic analgesic used
研究组 & 干预措施
dexmedetomidine and bupivacaine
Bupivacaine 50 mg and dexmedetomidine 1 microgram/kg
干预措施: dexmedetomidine (Drug)
dexmedetomidine and bupivacaine
Bupivacaine 50 mg and dexmedetomidine 1 microgram/kg
干预措施: bupivacaine (Drug)
Bupivacaine and placebo
Bupivacaine 100 mg and SF 10 ml
干预措施: dexmedetomidine (Drug)
Bupivacaine and placebo
Bupivacaine 100 mg and SF 10 ml
干预措施: bupivacaine (Drug)
结局指标
主要结局
the duration of sensorial block
时间窗: postoperative 1 day
pin-prick test
次要结局
- the first time analgesic required(postoperative 1 day)
研究者
Recep Aksu
associate professor
TC Erciyes University