A clinical study comparing early feeding with late feeding initiation in premature newborn babies with abnormal ultrasound Doppler blood flow in the umbilical arteries.
Not Applicable
Completed
- Conditions
- Health Condition 1: null- Preterm intrauterine growth restricted neonates below 33 weeks period of gestation with absent or reversed end diastolic flow on umbilical artery Doppler flow studies done antenatally
- Registration Number
- CTRI/2017/09/009641
- Lead Sponsor
- Vishal Vishnu Tewari
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 62
Inclusion Criteria
Intramural preterm IUGR neonates below 33 weeks with AREDF on UA Doppler and admitted to the NIC
Exclusion Criteria
Neonates, who were extramural, symmetric IUGR, or had antenatally suspected intestinal anomaly, lethal congenital anomaly, clinical suspicion of genetic aberration, needed invasive ventilation, inotropic support or extensive resuscitation and unavailable parent were excluded. Intramural preterm IUGR neonates < 27 weeks were also excluded.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Incidence of necrotizing enterocolitis (NEC) in neonates fed early versus late.Timepoint: From admission to discharge from the neonatal intensive acre unit (NICU)
- Secondary Outcome Measures
Name Time Method Secondary outcomes were incidence of FI, time to achieve adequate enteral intake allowing discontinuation of PN, time to attainment of full feeds, time to regain birth weight, incidence of LOS, duration of hospital stay and all-cause mortality.Timepoint: From admission to discharge from the neonatal intensive care unit (NICU)