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Clinical Trials/NCT02115945
NCT02115945
Completed
Early Phase 1

COMPARISON OF CONTINUOUS FEMORAL NERVE BLOCK AND PATIENT CONTROLLED EPIDURAL ANALGESIA AFTER TOTAL KNEE ARTHROPLASTY

Aydin Adnan Menderes University1 site in 1 country40 target enrollmentFebruary 2013

Overview

Phase
Early Phase 1
Intervention
Not specified
Conditions
Acute Postoperative Pain
Sponsor
Aydin Adnan Menderes University
Enrollment
40
Locations
1
Primary Endpoint
Persistent surgical pain after total knee arthroplasty assessed by VAS scale
Status
Completed
Last Updated
12 years ago

Overview

Brief Summary

Total knee prosthetic replacement causes severe postoperative pain. Various analgesic techniques have been used in pain control. Comparison of epidural and femoral nerve block is lacking, furthermore effect on chronic pain is unclear. The investigators aimed to compare the effects of epidural and femoral block on acute and chronic postoperative pain.

Detailed Description

Background and aim Total knee prosthetic replacement causes severe postoperative pain. Various analgesic techniques have been used in pain control. Comparison of epidural and femoral nerve block is lacking, furthermore effect on chronic pain is unclear. The investigators aimed to compare the effects of epidural and femoral block on acute and chronic postoperative pain. Methods The study was of randomized, prospective, and double-blind design and was conducted with 80 patients who had undergone total knee prosthetic replacement surgery with the insertion of a femoral nerve block or epidural block catheter to initiate postoperative analgesia. One-sided spinal anesthesia was performed in all the patients. Postoperative pain control was achieved with the administration via catheter using bupivacaine for patient-controlled analgesia. Acute postoperative pain was evaluated in the first 24 hours and chronic postoperative pain in the 1st and 3rd months following surgery. The anxiety/depression scale was used to assess anxiety and depression, the SF 12 test was used to evaluate quality of life, and the DN4 test was employed at patient visits at the 1st and 3rd months.

Registry
clinicaltrials.gov
Start Date
February 2013
End Date
March 2014
Last Updated
12 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Aydin Adnan Menderes University
Responsible Party
Principal Investigator
Principal Investigator

SINEM SARI

MD, Assistant Professor

Aydin Adnan Menderes University

Eligibility Criteria

Inclusion Criteria

  • Clinical diagnosis of total knee arthroplasty

Exclusion Criteria

  • Patients with pain syndromes
  • Patients using routinely medications for pain

Outcomes

Primary Outcomes

Persistent surgical pain after total knee arthroplasty assessed by VAS scale

Time Frame: 3 months

Secondary Outcomes

  • The anxiety and depression was evaluated with Hospital anxiety and depression scale.(3 months)

Study Sites (1)

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