Comparison of gradual return of consciousness and recovey features of sevoflurane and desflurane inhaled anaesthesia drugs in patients after long duration surgeries under general anaesthesia
Not Applicable
- Conditions
- Health Condition 1: I00-I99- Diseases of the circulatory systemHealth Condition 2: K00-K95- Diseases of the digestive systemHealth Condition 3: N00-N99- Diseases of the genitourinary systemHealth Condition 4: M00-M99- Diseases of the musculoskeletal system and connective tissueHealth Condition 5: C00-D49- NeoplasmsHealth Condition 6: E078- Other specified disorders of thyroidHealth Condition 7: J988- Other specified respiratory disorders
- Registration Number
- CTRI/2021/08/035860
- Lead Sponsor
- Commandant and Principal Command Hospital Air Force
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.ASA physical status Grade I ,II and III
2.Patients undergoing surgeries under General Anaesthesia lasting for more than 4 hours and planned for extubation after surgery
Exclusion Criteria
1.Significant cardiovascular, respiratory, hepatic, renal, neurologic, psychiatric or metabolic disease,Craniotomies and cardiac surgeries
2.ASA Grade > III
3.Any complication leading to deviation from the proposed anaesthesia plan and likely to prevent proper assessment of study variables.
4.Documented allergic reaction to the anaesthetic agent being used.
5.Patient on chronic opioid analgesic or chronic use of alcohol.
6.Patientâ??s refusal to participate in the study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare Desflurane and Sevoflurane with regards to emergence and recovery characteristics in patients undergoing prolonged surgeries under General Anaesthesia by comparing the â??Modified Aldrete Scoreâ?? between the two groups at 15, 30, 45 and 60 minutes after extubation.Timepoint: By comparing the â??Modified Aldrete Scoreâ?? between the two groups at baseline, 15, 30, 45 and 60 minutes after extubation.
- Secondary Outcome Measures
Name Time Method 1.Compare time to extubation, spontaneous eye opening and response to verbal commands after switching off the volatile agent. <br/ ><br> <br/ ><br>2.Compare the incidence of laryngospasm, emergence hypertension and postoperative nausea vomiting with use of both the anaesthetic agents. <br/ ><br>Timepoint: At 15 min, 30 min, 45 min and 60 min after extubation