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Potency and requirement of propofol for loss of consciousness in end-stage renal disease patients.

Not Applicable
Completed
Conditions
Diseases of The genitoruinary system
Registration Number
KCT0003734
Lead Sponsor
Soon Chun Hyang University Hospital Seoul
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
45
Inclusion Criteria

Aged = 20, American Society of Anestheisologists physical status I-II scheduled for elective surgery.

Exclusion Criteria

1. Patients with neurological dysfuction, history of central nervous system disease, psychological disease
2. Patients on medications affecting central nervous system such as anticonvulsants, hypnotics, analgesics
3. Abnormal liver function
4. Body mass index (BMI) > 30 kg/m2
5. A history of adverse drug reaction with propofol and local anesthetics
6. A history of allergic reaxction with peanuts
7. A history of kidney transplantation

Study & Design

Study Type
Observational Study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Potency and total amount of propofol for loss of consciousness are compared between end-stage renal disease patients and normal kidney function patients.
Secondary Outcome Measures
NameTimeMethod
Potency and total amount of propofol for loss of consciousness are compared between cervical epidural anesthesia with monitored anesthesia care and general anesthesia among end-stage renal disease patients.
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